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A simple assay was developed to estimate functional mannose-binding lectin (MBL) levels in serum based on the principle of yeast-induced bystander lysis of chicken erythrocytes (ChE). The assay is sensitive to inhibition by ethylene glycol bis-(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid (EGTA) (which allows alternative pathway activation), ethylene diamine tetraacetic acid (EDTA), mannose,
The extracellular matrix consists of structural macromolecules and other proteins with regulatory functions. An important family of the latter class of molecules found in most tissues is the small leucine-rich repeat proteins (SLRPs). We have previously shown that the SLRP fibromodulin binds directly to C1q and activates the classical pathway of complement. In the present study we further examine
An indirect 125I-labeled protein A assay for detection of cell surface-bound rat immunoglobulins is presented. The assay is quantitative and rapid and detects as little as 1 ng of cell surface-bound Ig. It discriminates between antibodies belonging to different IgG subclasses, IgM and IgA. We describe the production and specificity control of the reagents used and show that the test can be used fo
OBJECTIVES This study describes changes in high-frequency QRS components (HF-QRS) during percutaneous transluminal coronary angioplasty (PTCA) and compares the ability of these changes in HF-QRS and ST-segment deviation in the standard 12-lead electrocardiogram (ECG) to detect acute coronary artery occlusion. BACKGROUND Previous studies have shown decreased HF-QRS in the frequency range of 150–
Abstract The overarching aim of this paper is to investigate the importance of technological shifts and national macroeconomic preconditions for long term growth and structural transformation in various regions in a national regional system. Intrinsic to this, the issue and origin of divergence and convergence coming in repetitive waves in regional systems will be discussed as a possible contribut
There are a number of interpretations of the concept “integration” in Product Development (PD). Different sources tend to use different terminologies for describing the same phenomenon of integration, or use the same term for different purposes. This paper strives to capture the essence of the concept of “integration” within a product development project by looking for what is integrated and how i
This paper presents a solution to panoramic image stitching of two images with co- inciding optical centers, but unknown focal length and radial distortion. The algorithm operates with a minimal set of corresponding points (three) which means that it is well suited for use in any RANSAC style algorithm for simultaneous estimation of geometry and outlier rejection. Compared to a previous method for
Extremely large filled-aperture ground-based optical-IR telescopes, or ELTs, ranging from 20 to 100m in diameter, are now being proposed. The all-important choice of the aperture must clearly be driven by the potential science offered. We here highlight science goals from the Leiden Workshop in May 2001 suggesting that for certain critical observations the largest possible aperture - assumed to be
This chapter expands on three main topics. First, it is argued that the economic historical perspective may contribute to our understanding of present day development processes. Instead of advocating a one-size-fits-all model, an analytical framework is offered based on common traits from diverse examples. Second, the importance of agricultural change on the road towards sustained economic growth
Under the principle of freedom of contract, when two parties begin contract negotiations, they are under no obligation to actually arrive at an agreement and each one carries the risk for its own expenses and losses caused by the negotiations. However, even if the main rule says that each party bears the costs it might have incurred during the negotiations, if the parties do not reach an agreement
Case commentary | “Decision on the Apparent Conflict of Interests in relation to the Legal Representative of Victims a/0015/08...a/0035/08, Prosecutor v. Katanga and Ngudjolo Chui, Case No ICC-01/04–01/07, Pre-Trial Chamber I, 16 July 2008”
Popular Abstract in Swedish Utifrån epigrafiska källor analyserar avhandlingen Afrodites roll som ämbetsmannabeskyddarinna. Huvudmaterialet är 62 dedikationer till Afrodite: inskrifter från ämbetsmän eller dedikationer där gudinnan presenteras med ett epitet som alluderar på ett ämbete, t.ex. Afrodite Strategis, ‘Strategernas Afrodite’. Materialet visar att Afrodite dyrkades av ämbetsmän på ett paThrough the identification of a series of inscriptions, mainly datable to the Hellenistic era, a link between Aphrodite and the civic life and administration of the Greek poleis has come to light. The inscriptions in question are dedications to Aphrodite through which magistrates of various cities and varying status express their devotion to the goddess. In certain dedications, the goddess is even
CONTEXT: It is important to identify patients at highest risk of fractures. OBJECTIVE: To compare the separate and combined performances of bone-related genetic risk scores (GRSs) for prediction of forearm, hip and vertebral fractures separately, as well as of trabecular and cortical bone microstructure parameters separately. DESIGN, SETTING, AND PARTICIPANTS: Using 1103 single nucleotide polymorp
Background: Tinnitus sufferers commonly report concentration difficulties. Despite several previous studies investigating this, the underlying cause and the role of hearing status remains unclear. Purpose: To investigate whether there are any differences between normal hearing individuals with and without tinnitus in terms of working memory capacity, and whether working memory capacity correlates
