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Dose-related changes in retinal function and PKC-alpha expression in rabbits on vigabatrin medication : Effect of vigabatrin in the rabbit eye.

BACKGROUND: To investigate, in a rabbit model, the effect of two different doses of vigabatrin (VGB) on retinal function and morphology. METHODS: Twenty-nine rabbits of mixed strain were divided into two groups, receiving either high-dose (n = 15) or low-dose (n = 14) oral VGB treatment (cumulative dose 29.8 +/- 2.9 g and 14.2 +/- 0.6 g respectively). Ten rabbits receiving water served as control

Implementation and validation of a new soot model and application to aeroengine combustors

The modeling of soot formation and oxidation under industrially relevant conditions has made significant progress in recent years. Simplified models introducing a small number of transport equations into a CFD Code have been used with some success in research configurations simulating a reciprocating diesel engine. Soot formation and oxidation in the turbulent flow is calculated on the basis of a

Experimental vitreous tamponade using polyalkylimide hydrogel

To evaluate polyalkylimide as a possible vitreous tamponading agent. A 20-gauge pars plana vitrectomy and posterior vitreous detachment were performed in the right eye of six pigmented rabbits. Approximately 1 ml of viscoelastic gel, polyalkylimide (Bio-AlcamidA (R)) was thereafter injected into the vitreous space. Full-field ERG and intraocular pressure (IOP, Tonopen) was measured pre-and postope

Pre-treatment of wastewater sludge before anaerobic digestion - hygienisation, ultrasonic treatment and enzyme dosing

Pre-treatment of sludge before anaerobic digestion can increase methane production and degradation of organic matter. There are various pre-treatment methods for this purpose. Anaerobic digestion tests were performed for comparison of three pre-treatment methods (hygienisation, ultrasonic treatment and enzyme dosing) used separately or in combination on biosludge and mixed sludge. COD solubilisati

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Abstract in Danish En paragraf i serviceloven giver pårørende mulighed for at få pasningsorlov, når deres nærtstående familiemedlem er indlagt. Men paragraffen er ikke kendt af så mange.

Det kodade meddelandet - Metaforisk interaktion och dödslängtan i Per Olov Enquists Nedstörtad ängel

Per Olov Enquist's 1985 novel Nedstörtad ängel (Downfall) is, despite its modest proportions, one of the most poetically powerful and intriguing works in his oeuvre. It consists of a number of disparate stories which are presented as intertwined fragments. In this article I argue that the novel as a whole creates its meaning in the manner of a large-scale metaphor, in which the different stories s

Survival of patients on home mechanical ventilation: A nationwide prospective study.

Home mechanical ventilation (HMV) is increasingly used as a therapeutic option to patients with symptomatic chronic hypoventilation. There is, however, a paucity of solid data on factors that could affect prognosis in patients on home ventilation. In the present study, our aim was to study several factors in these patients with potential influence on survival. We examined 1526 adult patients from

On approximate policy iteration for continuous-time systems

We propose a new algorithm for feedback nonlinear synthesis. The algorithm computes suboptimal solutions, with bounds on suboptimality, to the Hamilton-Jacobi-Bellman equation. For systems that are modeled with polynomials the computations can be done efficiently via semidefinite programming. To illustrate the strength of the proposed method, we computesmooth stabilizing feedback controllers for s