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Pesticide exposure among organic and conventional smallholder farmers in Costa Rica and Uganda : biomarker evidence on exposure determinants

BACKGROUND: Pesticides play a crucial role in pest control; however, exposure remains high, particularly among smallholder farmers in low-income and middle-income countries (LMICs) with little access to pesticide safety training. This study aimed to provide comparative biomarker-based evidence from Latin America and Africa and identify actionable determinants of exposure to inform context-specific

Applying a wicked problem model to strategic development in UK higher education

This reflective commentary, based on long-term experience in UK higher education, proposes a novel approach to using a wicked problem model to develop policy and practice within higher education. The aim of this approach is to reframe the narrative of strategic development to acknowledge the complexity of cultural change and the importance of stakeholder consultation to build trust, moving away fr

Universal conductance fluctuations and phase-coherent transport in a semiconductor Bi2O2Se nanoplate with strong spin-orbit interaction

We report on phase-coherent transport studies of a Bi2O2Se nanoplate and on observation of universal conductance fluctuations and spin-orbit interaction induced reduction in fluctuation amplitude in the nanoplate. Thin-layered Bi2O2Se nanoplates are grown by chemical vapor deposition (CVD) and transport measurements are made on a Hall-bar device fabricated from a CVD-grown nanoplate. The measureme

Directional Negative Thermal Expansion and Large Poisson Ratio in CH 3 NH 3 PbI 3 Perovskite Revealed by Strong Coherent Shear Phonon Generation

Despite the enormous amount of attention CH 3 NH 3 PbI 3 has received, we are still lacking an in-depth understanding of its basic properties. In particular, the directional mechanical and structural characteristics of this material have remained elusive. Here, we investigate these properties by monitoring the propagation of longitudinal and shear phonons following the absorption of a femtosecond

Mechanistic study of the reaction of CH 2 F 2 with Cl atoms in the absence and presence of CH 4 or C 2 H 6 : Decomposition of CHF 2 OH and fate of the CHF 2 O radical

To assess the atmospheric fate of fluorinated compounds, chamber experiments were performed with Fourier transform infrared spectroscopy investigating the products of difluoromethane, CH 2 F 2 , at 296 ± 2 K. The reactions were initiated by reaction of CH 2 F 2 with Cl atoms in the absence and presence of CH 4 or C 2 H 6 in air or O 2 . No evidence of formation of the fluorinated alcohol, CHF 2 O

Parental separation/divorce in childhood and tobacco smoking in adulthood : A population-based study

Aims: The aim was to investigate associations between the experience of parental separation/divorce in childhood and tobacco smoking in adulthood, adjusting for economic stress in childhood and adulthood and psychological health (General Health Questionnaire GHQ12). Methods: The 2012 public-health survey in Skåne, southern Sweden, is a cross-sectional postal questionnaire population-based study wi

Factors associated with non-Attendance at exercise-based cardiac rehabilitation

Background: Despite its well-established positive effects, exercise-based cardiac rehabilitation (exCR) is underused in patients following an acute myocardial infarction (AMI). The aim of the study was to identify factors associated with non-Attendance at exCR in patients post-AMI in a large Swedish cohort. Methods: A total of 31,297 patients who have suffered an AMI, mean age 62.4 ± 4 years, were

Genetically Determined Risk of Depression and Functional Outcome After Ischemic Stroke

Background and Purpose- Psychosocial factors can have implications for ischemic stroke risk and recovery. This study investigated the effect of genetically determined risk of depression on these outcomes using the Mendelian randomization (MR) framework. Methods- Genetic instruments for risk of depression were identified in a discovery genome-wide association study of 246 363 cases and 561 190 cont

Correction of Fabry-Pérot interference effects in phase and amplitude pulse shapers based on liquid crystal spatial light modulators

Broadband femtosecond laser pulses manipulated by pulse shapers based on a liquid crystal spatial light modulator (LC-SLM) inevitably experience periodic spectral distortions due to Fabry-Perot interference effects within the LC-SLM. We present a method, applicable to phase and amplitude pulse shapers based on dual LC-SLMs, that enables the calibration and suppression of the undesired spectral int

Te incorporation and activation as n-type dopant in self-catalyzed GaAs nanowires

Dopant atoms can be incorporated into nanowires either via the vapor-liquid-solid mechanism through the catalyst droplet or by the vapor-solid growth on the sidewalls. Si is a typical n-type dopant for GaAs, but in nanowires it often suffers from a strongly amphoteric nature in the vapor-liquid-solid process. This issue can be avoided by using Te, which is a promising but less common alternative f

Active Posts in Deterministic Lateral Displacement Devices

Using electrically connected metal-coated posts in a deterministic lateral displacement (DLD) device and applying electric fields, electrokinetics is used to tune separations, significantly decrease the critical size for separation, and increase the dynamic range with switching times on the order of seconds. The strength of DLD stems from its binary behavior. To first approximation, particles move

Inequalities in the economic consequences of depression and anxiety in Europe : a systematic scoping review

BACKGROUND: Depression and anxiety are associated with adverse outcomes in educational achievements and economic performances. Moreover, the prevalence of these disorders is unequally distributed among different population subgroups. Our objective is to investigate whether the economic consequences of depression and anxiety differ between population subgroups of different gender, socioeconomic sta

HbA1c Levels Do Not Affect Long-Term Outcome After Open Trigger Finger Release in Individuals With Diabetes Mellitus

BACKGROUND: Trigger finger surgery typically has a successful outcome, also in patients with diabetes mellitus (DM). However, the impact of glycemic control on long-term outcomes after open trigger finger release (OTFR) remains unclear. This study examines whether high hemoglobin A1c (HbA1c) levels affect patient-reported outcome (PRO) following OTFR in individuals with type 1 diabetes mellitus (T

Diversity in genetic risk of recurrent stroke : a genome-wide association study meta-analysis

INTRODUCTION: Stroke is a leading cause of death and disability worldwide. Recurrent strokes are seven times more lethal than initial ones, with 54% leading to long-term disability. Substantial recurrent stroke risk disparities exist among ancestral groups. Notably, Africans face double the risk and higher fatality rates compared to Europeans. Although genetic studies, particularly GWAS, hold prom

Impact of increasing overweight and obesity on breathlessness : a review

PURPOSE OF REVIEW: To summarize and critically interpret new evidence (from the last 12-18 months) on the associations between obesity and breathlessness, including epidemiology, physiological mechanisms, diagnostic challenges, and treatment approaches.RECENT FINDINGS: Multiple large cohorts confirm that obesity is one of the strongest independent predictors of exertional breathlessness. Recent wo

Comparative effectiveness of dolutegravir + lamivudine versus three-drug regimens in Swedish clinical practice : a nationwide study

Introduction: HIV guidelines recommend switching from a three-drug regimen (3DR) to dolutegravir + lamivudine (DTG+3TC) for eligible individuals. This retrospective national cohort study used Swedish InfCareHIV registry data to evaluate long-term outcomes of adults with HIV RNA <50 copies/ml who switched to DTG+3TC or a guideline-recommended 3DR between July 2019 and May 2023 in routine clinical c

Dynamics of long-term adherence to lipid-lowering therapy in patients after myocardial infarction

Despite recommendations to use oral lipid-lowering therapies (LLT) in secondary prevention of atherosclerotic cardiovascular disease, numerous studies have shown substantial under-utilization. We assessed long-term persistence and dynamics of adherence to oral LLTs in patients after their first ever myocardial infarction (MI) in Sweden. A total of 83,407 patients with a MI (2010–2017) and who were

Poor long-term cardiovascular risk factor management after acute coronary syndrome : An observational cohort study

Background: Cardiovascular risk factor control reduces the risk of recurrent events after acute coronary syndrome (ACS). Long-term post-ACS management is poorly studied. Objectives: To assess frequency of low-density lipoprotein cholesterol (LDL-C) and systolic blood pressure (SBP) monitoring and target achievement during 3 years post-ACS. Methods: Data from all patients hospitalized for ACS in Up

Medication adherence after myocardial infarction : Predictors, mortality and cardiovascular outcomes

Background and aims Secondary prevention medications after myocardial infarction (MI) are crucial for reducing mortality and cardiovascular events, however, adherence is often suboptimal. This study aimed to investigate predictors of adherence, and clinical outcomes among STEMI and NSTEMI survivors in Sweden. Methods This nationwide cohort study included patients hospitalized with MI between 2017